Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL28090978 | 0.97 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL27589214 | 0.93 | ALDH1A1 (0.64) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL27589213 | 0.93 | ALDH1A1 (0.64) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL11540830 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| SCHEMBL810729 | 0.90 | ALDH1A1 (0.67) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL30137691 | 0.89 | ALDH1A1 (0.82) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL29276287 | 0.89 | ALDH1A1 (0.82) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL8150900 | 0.89 | ALDH1A1 (0.82) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Hydrochloric Acid SCHEMBL27462859 | 0.88 | ALDH1A1 (0.64) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Anthranilic Acid SCHEMBL10667669 | 0.86 | MAPT (0.55) | ALDH1A1ALOX15KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401321-B1 | CURED PERFLUOROELASTOMER ARTICLE | DU PONT (US) | 2013-09-18 | — | — | EP | disclosed |
| US-8318850-B2 | Cured perfluoroelastomer article | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-27 | — | — | US | disclosed |
| EP-2401321-A2 | CURED PERFLUOROELASTOMER ARTICLE | DuPont Performance Elastomers L.L.C. (US) | 2012-01-04 | — | — | EP | disclosed |
| CN-101151294-B | Epoxy resin composition | ASAHI CHEMICAL CORP (JP) | 2011-02-09 | — | — | CN | disclosed |
| EP-1867672-B1 | EPOXY RESIN COMPOSITION | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010099057-A2 | CURED PERFLUOROELASTOMER ARTICLE | DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) | 2010-09-02 | — | — | WO | disclosed |
| US-20100216933-A1 | CURED PERFLUOROELASTOMER ARTICLE | DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20090032286-A1 | Epoxy Resin Composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-101151294-A | Epoxy resin composition | ASAHI CHEMICAL CORP (JP) | 2008-03-26 | — | — | CN | disclosed |
| EP-1867672-A1 | EPOXY RESIN COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-20020146650-A1 | Photographic processing element and image forming method by the use thereof | KONICA CORPORATION (JP) | 2002-10-10 | — | — | US | disclosed |
| US-6455235-B1 | PHOTOGRAPHIC PROCESSING ELEMENT COMPRISING PRECURSOR OF COLOR DEVELOPING AGENT | KONICA CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |
| CN-1300962-A | Photo processing element and imaging method therefor | KONISHIROKU PHOTO IND (JP) | 2001-06-27 | — | — | CN | disclosed |
| EP-1109064-A1 | Photographic processing element and image forming method by the use thereof | KONICA CORPORATION (JP) | 2001-06-20 | — | — | EP | disclosed |