Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842060 | 0.88 | TNF (0.37) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1843018 | 0.88 | ABL1 (0.39) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1849172 | 0.87 | TNF (0.37) | ABL1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1843261 | 0.87 | ABL1 (0.38) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1843503 | 0.86 | ACHE (0.42) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2180521 | 0.86 | KDM4E (0.37) | ABL1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1843304 | 0.86 | ACHE (0.40) | ABL1NPC1RAB9ASMN1; SMN2 | |
| Lithium Ion SCHEMBL1842051 | 0.86 | ACHE (0.36) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1842666 | 0.86 | ACHE (0.42) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2180195 | 0.86 | ABL1 (0.35) | ABL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321309-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2011-05-18 | — | — | EP | disclosed |
| WO-2009156966-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |