Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842573 | 0.86 | NPC1 (0.38) | NPC1RAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL1852504 | 0.85 | ADORA2A (0.43) | NPC1RAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL1841862 | 0.83 | HTT (0.36) | NPC1RAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL2180655 | 0.83 | NPC1 (0.36) | NPC1RAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL2179043 | 0.83 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1845578 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1LMNASMN1; SMN2GABRG2GABRB3 | |
| SCHEMBL2180653 | 0.73 | GPBAR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL1707976 | 0.71 | ADORA2A (0.51) | NPC1RAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL1843794 | 0.71 | ABL1 (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1841115 | 0.71 | MEN1 (0.33) | MEN1MAPTHTTKMT2ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321309-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2011-05-18 | — | — | EP | disclosed |
| WO-2009156966-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |