Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.31 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.31 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283081 | 0.81 | PIK3CD (0.41) | ALDH1A1LMNATGFBR1MAPK14 | |
| SCHEMBL1842575 | 0.79 | NPC1 (0.34) | SMN1; SMN2ALDH1A1LMNAGABRG2GABRB3 | |
| SCHEMBL1842573 | 0.78 | NPC1 (0.38) | SMN1; SMN2ALDH1A1LMNAHCRTR1HCRTR2 | |
| SCHEMBL2180653 | 0.76 | GPBAR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL2180655 | 0.76 | NPC1 (0.36) | SMN1; SMN2ALDH1A1LMNAHCRTR1HCRTR2 | |
| SCHEMBL1852504 | 0.76 | ADORA2A (0.43) | SMN1; SMN2ALDH1A1LMNAADORA1 | |
| SCHEMBL1841115 | 0.76 | MEN1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL2179043 | 0.75 | NPC1 (0.42) | SMN1; SMN2 | |
| SCHEMBL1840097 | 0.72 | GABRG2 (0.36) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL30755415 | 0.69 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | US | disclosed |
| EP-2321309-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2011-05-18 | — | — | EP | disclosed |
| WO-2009156966-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166088-A1 | BENZOTHIAZOLES AND AZA-ANALOGUES THEREOF USE AS ANTIBACTERIAL AGENTS | TOP2B, TOP1, POLI | SMN1; SMN2 4463/4885ALDH1A1 2009/4885LMNA 3229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.