⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020773 | 0.92 | — | — | |
| SCHEMBL5159668 | 0.89 | TRIM24 (0.47) | — | |
| SCHEMBL18634 | 0.84 | — | — | |
| SCHEMBL1191601 | 0.67 | — | — | |
| SCHEMBL13588344 | 0.65 | — | — | |
| SCHEMBL9323692 | 0.65 | — | — | |
| SCHEMBL276387 | 0.65 | — | — | |
| SCHEMBL10363679 | 0.65 | CRBN (0.33) | — | |
| SCHEMBL2829 | 0.65 | — | — | |
| SCHEMBL2784295 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2729 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077244-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | HOTSPOT THERAPEUTICS, INC. (US) | 2024-04-11 | — | — | WO | claimed |
| US-10829512-B2 | Selective disulfidation reagent using nitrogen-containing compound and method for producing disulfide-containing compound | TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) | 2020-11-10 | — | — | US | claimed |
| CN-107108660-B | Boronic acid derivatives | 默克专利股份公司 | 2020-09-15 | — | — | CN | claimed |
| EP-3201205-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | claimed |
| US-10640520-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2020-05-05 | — | — | US | claimed |
| US-20180179231-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-06-28 | — | — | US | claimed |
| EP-3201205-A1 | BORONIC ACID DERIVATIVES | Merck Patent GmbH (DE) | 2017-08-09 | — | — | EP | claimed |
| EP-2240179-B1 | IMIDAZOPYRIDAZINE AS PAR1 INHIBITORS, THEIR MANUFACTURE AND THEIR APPLICATION AS MEDICINE | SANOFI SA (FR) | 2016-08-17 | — | — | EP | claimed |
| WO-2016050355-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-04-07 | — | — | WO | claimed |
| EP-2240486-B1 | TRIAZOLIUM SALTS AS PAR1 INHIBITORS, THEIR MANUFACTURE AND THEIR APPLICATION AS MEDICINE | SANOFI SA (FR) | 2015-09-09 | — | — | EP | claimed |
| US-5204344-A | (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes | MERCK FROSST CANADA, INC. (CA) | 1993-04-20 | — | — | US | claimed |
| US-5190968-A | Antiinflammatory | MERCK FROSST CANADA, INC. (CA) | 1993-03-02 | — | — | US | claimed |
| US-5137886-A | Agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-11 | — | — | US | claimed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | claimed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | claimed |
| EP-0433001-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-19 | — | — | EP | claimed |
| EP-0373891-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | claimed |
| US-4578474-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1986-03-25 | — | — | US | claimed |
| EP-0042639-B1 | AZIDO, IMIDO, AMIDO AND AMINO DERIVATIVES OF MERCAPTOACYL PROLINES AND PIPECOLIC ACIDS HAVING HYPOTENSIVE ACTIVITY | E.R. Squibb & Sons, Inc. (US) | 1984-08-22 | — | — | EP | claimed |
| EP-0042639-A2 | Azido, imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids having hypotensive activity | E.R. Squibb & Sons, Inc. (US) | 1981-12-30 | — | — | EP | claimed |