SCHEMBL184290

SCHEMBL184290

CC(CC#N)N=NC(C)CC#N

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3036792 1.00 TSHR (0.38) TSHRALDH1A1CYP1A2MAPK1
SCHEMBL1847034 0.77
SCHEMBL132909 0.75 ALDH1A1 (0.35) ALDH1A1
SCHEMBL1191661 0.73
SCHEMBL28724081 0.73
SCHEMBL28724083 0.73
SCHEMBL1345692 0.72
SCHEMBL11118613 0.71
SCHEMBL2201425 0.71 TSHR (0.52) TSHRALDH1A1
SCHEMBL2201423 0.71 TSHR (0.52) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753785-B1 PROCESS FOR PREPARATION OF POLYSACCHARIDE-GRAFTED POLYMER PARTICLES UNILEVER PLC (GB) 2016-11-09 EP claimed
EP-1572767-B1 FABRIC CARE COMPOSITION UNILEVER PLC (GB) 2008-10-15 EP claimed
US-9334469-B2 Fabric treatment compositions comprising targeted benefit agents CONOPCO, INC. (US) 2016-05-10 US disclosed
US-9169459-B2 Fabric treatment compositions comprising target benefit agents CONOPCO, INC. (US) 2015-10-27 US disclosed
US-20130210697-A1 FABRIC TREATMENT COMPOSITIONS COMPRISING TARGET BENEFIT AGENTS CONOPCO, INC., D/B/A UNILEVER 2013-08-15 US disclosed
US-8158571-B2 Fabric treatment composition comprising a core-shell particle bound to a phthalate-containing polymer CONOPCO INC. (US) 2012-04-17 US disclosed
EP-1954796-B1 IMPROVEMENTS RELATING TO FABRIC TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2012-01-04 EP disclosed
EP-2319910-A2 Improvements relating to fabric treatment compositions Unilever PLC (GB) 2011-05-11 EP disclosed
US-20100216684-A1 PERFUME PARTICLES CONOPCO, INC. D/B/A UNILEVER 2010-08-26 US disclosed
US-7703916-B2 Polarizing plate with melanin HOYA OPTICAL LABS OF AMERICA, INC. 2010-04-27 US disclosed
US-20080144176-A1 Polarizing Plate With Melanin HOYA OPTICAL LABS OF AMERICA, INC. 2008-06-19 US disclosed
EP-0380518-B1 MELANIN CONTAINING HYDROPHILIC CONTACT LENSES PHOTOPROTECTIVE TECHN INC (US) 1996-07-31 EP disclosed
US-5187207-A Melanin hydrophilic contact lenses PHOTOPROTECTIVE TECHNOLOGIES, INC. (US) 1993-02-16 US disclosed
US-5116884-A Melanin hydrophilic contact lenses PHOTOPROTECTIVE TECHNOLOGY INCORPORATED (US) 1992-05-26 US disclosed
US-5112883-A Medium incorporating melanin as an absorbing pigment against electromagnetic radiation PHOTOPROTECTIVE TECHNOLOGIES INCORPORATED (US) 1992-05-12 US disclosed
US-5047447-A Medium incorporating melanin as an absorbing pigment for protection against electromagnetic radiation PHOTOPROTECIVE TECHNOLOGIES INCORPORATED (US) 1991-09-10 US disclosed
EP-0380518-A4 MELANIN HYDROPHILIC CONTACT LENSES 1991-05-22 EP disclosed
EP-0380518-A1 MELANIN HYDROPHILIC CONTACT LENSES. PHOTOPROTECTIVE TECHN INC (US) 1990-08-08 EP disclosed
EP-0311290-A2 Melanin hydrophilic contact lenses PHOTOPROTECTIVE TECHNOLOGIES INC. (US) 1989-04-12 EP disclosed
WO-1989001639-A1 MELANIN HYDROPHILIC CONTACT LENSES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1989-02-23 WO disclosed