SCHEMBL23554228

SCHEMBL23554228

CCCCCCCCCCCCCCCCCCS(=O)(=O)NCCCCn1c(CC)nc2c(N)nc3ccccc3c21

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.78
TLR8 Q9NR97 10/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25636046 0.96 TLR7 (0.80) TLR7TLR8
SCHEMBL13721540 0.94 TLR7 (0.68) TLR7TLR8
SCHEMBL13722028 0.93 TLR7 (0.82) TLR7TLR8
SCHEMBL18680036 0.91 TLR7 (0.85) TLR7TLR8
SCHEMBL18429392 0.90 TLR7 (0.86) TLR7TLR8
SCHEMBL13722011 0.90 TLR7 (0.70) TLR7TLR8
SCHEMBL13721476 0.90 TLR7 (0.63) TLR7TLR8
SCHEMBL13721979 0.90 TLR7 (0.63) TLR7TLR8
SCHEMBL14516472 0.88 TLR7 (0.70) TLR7TLR8
SCHEMBL13721633 0.88 TLR7 (0.66) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372442-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll-like Receptor(\"TLR\") Agonist Prodrugs Useful In The Treatment of Cancer and Methods Thereof NAMMI THERAPEUTICS, INC. 2023-11-23 US disclosed
US-20230372442-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll-like Receptor(\"TLR\") Agonist Prodrugs Useful In The Treatment of Cancer and Methods Thereof NAMMI THERAPEUTICS, INC. 2023-11-23 US disclosed
US-20230277621-A1 Formulated and/or co-formulated liposome compositions containing toll-like receptor (\"TLR\") agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230277621-A1 Formulated and/or co-formulated liposome compositions containing toll-like receptor (\"TLR\") agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. 2023-09-07 US disclosed
US-11744874-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. (US) 2023-09-05 US disclosed
US-11744874-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. (US) 2023-09-05 US disclosed
US-20230270819-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll--Like Receptor (\"TLR\") Agonist Prodrugs Useful In The Treatment of Cancer and Methods Thereof NAMMI THERAPEUTICS, INC. 2023-08-31 US disclosed
US-20230270819-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll--Like Receptor (\"TLR\") Agonist Prodrugs Useful In The Treatment of Cancer and Methods Thereof NAMMI THERAPEUTICS, INC. 2023-08-31 US disclosed
US-11679141-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
US-11679141-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
US-20220193187-A1 Formulated and/or co-furmulated liposome compositions containing toll-like receptor (\"TLR\") agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. 2022-06-23 US disclosed
US-20210187066-A1 Formulated and/or co-formulated liposome compositions containing toll-like receptor (\"TLR\") agonist prodrugs useful in the treatment of cancer and methods thereof NAMMI THERAPEUTICS, INC. 2021-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744874-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof TLR1, TLR4, TLR7 TLR7 3/4885TLR8 8/4885
US-20230372442-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll-like Receptor(\"TLR\") Agonist Prodrugs Useful In The Treatment of Cancer and Methods Thereof TLR1, TLR7, TLR4 TLR7 2/4885TLR8 8/4885
US-20220193187-A1 Formulated and/or co-furmulated liposome compositions containing toll-like receptor (\"TLR\") agonist prodrugs useful in the treatment of cancer and methods thereof TLR1, TLR9, TLR4 TLR7 4/4885TLR8 8/4885
US-20230270819-A1 Formulated and/or Co-Formulated Liposome Compositions Containing Toll--Like Receptor (\"TLR\") Agonist Prodrugs Useful In The Treatment of Cancer and Methods Thereof TLR1, TLR7, TLR4 TLR7 2/4885TLR8 8/4885
US-11679141-B2 Formulated and/or co-formulated liposome compositions containing toll-like receptor (“TLR”) agonist prodrugs useful in the treatment of cancer and methods thereof TLR1, TLR4, TLR7 TLR7 3/4885TLR8 8/4885
US-20230277621-A1 Formulated and/or co-formulated liposome compositions containing toll-like receptor (\"TLR\") agonist prodrugs useful in the treatment of cancer and methods thereof TLR1, TLR7, TLR4 TLR7 2/4885TLR8 8/4885
US-20210187066-A1 Formulated and/or co-formulated liposome compositions containing toll-like receptor (\"TLR\") agonist prodrugs useful in the treatment of cancer and methods thereof TLR1, TLR7, TLR4 TLR7 2/4885TLR8 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.