SCHEMBL18429488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3955009	0.92	SYK (0.57)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL9222706	0.92	MAPT (0.52)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL25277569	0.90	HTT (0.54)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL6046926	0.89	SYK (0.54)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL20094984	0.88	ALDH1A1 (0.49)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL25376237	0.88	HTT (0.55)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL7308592	0.88	SYK (0.53)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL31258268	0.88	SYK (0.53)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL7431128	0.87	HTT (0.60)	SYKIDO1HTTMEN1KMT2A
	SCHEMBL4924340	0.86	HTT (0.56)	SYKIDO1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.