SCHEMBL1842972

SCHEMBL1842972

Nc1c(NCCN2CCOCC2)nn2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
TOP2A P11388 1/20 0.48
LMNA P02545 5/20 0.46
CYP3A4 P08684 5/20 0.46
KDM4E B2RXH2 4/20 0.46
HSD17B10 Q99714 4/20 0.46
CYP1A2 P05177 4/20 0.46
CYP2D6 P10635 4/20 0.46
GAA P10253 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
CHRM1 P11229 1/20 0.46
CNR1 P21554 1/20 0.46
ACHE P22303 1/20 0.46
HTR2B P41595 1/20 0.46
KCNH2 Q12809 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MKNK1 Q9BUB5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1840278 0.99 SMN1; SMN2 (0.48) SMN1; SMN2TOP2ALMNACYP3A4KDM4E
SCHEMBL1841548 0.88 KAT2B (0.48) TOP2AKDM4EHSD17B10GAAACHE
Hydrochloric Acid SCHEMBL1842069 0.87 KAT2B (0.47) TOP2AKDM4EHSD17B10GAAACHE
SCHEMBL1842861 0.87 KAT2B (0.49) TOP2AKDM4EHSD17B10GAAACHE
SCHEMBL1841847 0.86 KAT2B (0.51) TLR9
SCHEMBL1844920 0.85 LCK (0.44) CYP3A4KDM4EHSD17B10CYP2D6GAA
Hydrochloric Acid SCHEMBL1839969 0.85 KAT2B (0.50) TLR9
SCHEMBL10118459 0.85 DRD2 (0.48)
SCHEMBL26010421 0.85 KAT2B (0.39) CYP3A4KDM4ECHRM1KCNH2MEN1
SCHEMBL3835753 0.83 KAT2B (0.39) SMN1; SMN2TOP2ALMNACYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1792606-B1 Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine OREAL (FR) 2011-05-18 EP claimed
EP-1792606-A1 Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine L'Oréal (FR) 2007-06-06 EP claimed
EP-1792606-B1 Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine OREAL (FR) 2011-05-18 EP disclosed
EP-1792606-A1 Composition for dyeing keratinic fibers comprising at least one derivative of 3-amino pyrazolopyridine L'Oréal (FR) 2007-06-06 EP disclosed