Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 1.00 |
| ▸ | MAOB | P27338 | 5/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429785 | 0.89 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL10991891 | 0.89 | MAOB (0.80) | APPMAOBNR4A2MAOA | |
| SCHEMBL14612831 | 0.84 | APP (0.80) | APPMAOBRXRARXRB | |
| SCHEMBL3624903 | 0.82 | MAOB (0.69) | APPMAOBNR4A2MAOA | |
| SCHEMBL11600066 | 0.82 | MAOB (0.69) | APPMAOBNR4A2MAOA | |
| SCHEMBL11727989 | 0.82 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL3618224 | 0.82 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL5511971 | 0.82 | MAOB (0.69) | APPMAOBNR4A2MAOA | |
| SCHEMBL8942088 | 0.80 | MAOB (0.73) | APPMAOBNR4A2MAOA | |
| SCHEMBL11664961 | 0.80 | MAOB (0.73) | APPMAOBNR4A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581565-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | Beijing Zhibo Bio-Medical Technology Co., Ltd. (CN) | 2019-12-18 | — | — | EP | disclosed |
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | ZHANG ZHIYONG (CN) | 2017-02-09 | — | — | US | disclosed |
| CN-103724207-B | Phenylbenzyl ether derivative and its preparation method and application | 北京智博高科生物技术有限公司 | 2016-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | APP, PSEN1, PSEN2 | APP 1/4885MAOB 264/4885NR4A2 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.