Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.69 |
| ▸ | APP | P05067 | 2/20 | 0.69 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600066 | 1.00 | MAOB (0.69) | MAOBAPPNR4A2LMNACYP1A2 | |
| SCHEMBL10991891 | 0.91 | MAOB (0.80) | MAOBAPPNR4A2LMNAMAOA | |
| SCHEMBL5633306 | 0.89 | APP (0.79) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL11578826 | 0.89 | APP (0.79) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL416484 | 0.87 | NR4A2 (0.56) | MAOBAPPNR4A2LMNACYP1A2 | |
| SCHEMBL11314200 | 0.86 | MAOB (0.67) | MAOBAPPNR4A2LMNAMAOA | |
| SCHEMBL5511971 | 0.83 | MAOB (0.69) | MAOBAPPNR4A2LMNAMAOA | |
| SCHEMBL10494806 | 0.83 | APP (0.70) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL22596639 | 0.83 | APP (0.70) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL5633288 | 0.83 | APP (0.70) | APPLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270311-A | [1,2,4]-Triazolo[1,5-a]and pyrazolo[2,3-a][1,3,5]triazine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | claimed |
| CN-1056879-A | Pyrrole derivative and preparation method thereof | ICI PLC (GB) | 1991-12-11 | — | — | CN | claimed |
| EP-0459702-A1 | Azole Derivatives | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | claimed |
| EP-2036878-B1 | PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-7745669-B2 | Process for production of alcohol compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090259074-A1 | PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-10-15 | — | — | US | disclosed |
| EP-2036878-A1 | PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-5356894-A | Adenosine antagonists | SYNGENTA LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| US-5270311-A | [1,2,4]-Triazolo[1,5-a]and pyrazolo[2,3-a][1,3,5]triazine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| CN-1056879-A | Pyrrole derivative and preparation method thereof | ICI PLC (GB) | 1991-12-11 | — | — | CN | disclosed |
| EP-0459702-A1 | Azole Derivatives | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259074-A1 | PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND | XDH, ADH5, ADH1A | MAOB 499/4885APP 3660/4885NR4A2 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.