Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 1.00 |
| ▸ | RXRA | P19793 | 2/20 | 0.59 |
| ▸ | RXRB | P28702 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271017 | 1.00 | APP (1.00) | APPRXRARXRBMAOBCA12 | |
| SCHEMBL2399080 | 0.89 | APP (0.80) | APPRXRARXRBMAOBCA12 | |
| SCHEMBL18429785 | 0.89 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL11601389 | 0.82 | APP (0.69) | APPRXRARXRBMAOBCA12 | |
| SCHEMBL3618116 | 0.82 | APP (0.69) | APPRXRARXRBMAOBCA12 | |
| SCHEMBL3618224 | 0.82 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL11727989 | 0.82 | APP (1.00) | APPRXRARXRB | |
| SCHEMBL668783 | 0.81 | APP (0.68) | APPMAOB | |
| SCHEMBL14612831 | 0.80 | APP (0.80) | APPRXRARXRBMAOB | |
| SCHEMBL21568939 | 0.80 | MAOB (0.67) | APPRXRARXRBMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581565-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | Beijing Zhibo Bio-Medical Technology Co., Ltd. (CN) | 2019-12-18 | — | — | EP | disclosed |
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | ZHANG ZHIYONG (CN) | 2017-02-09 | — | — | US | disclosed |
| CN-103724207-B | Phenylbenzyl ether derivative and its preparation method and application | 北京智博高科生物技术有限公司 | 2016-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | APP, PSEN1, PSEN2 | APP 1/4885RXRA 482/4885RXRB 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.