Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.68 |
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342895 | 0.88 | IDO1 (0.64) | APPIDO1TSHRMAOB | |
| SCHEMBL649020 | 0.88 | IDO1 (0.64) | APPIDO1TSHRMAOB | |
| SCHEMBL508682 | 0.88 | CYP3A4 (0.64) | APPIDO1CYP3A4TSHR | |
| SCHEMBL15271017 | 0.81 | APP (1.00) | APPMAOB | |
| SCHEMBL18429784 | 0.81 | APP (1.00) | APPMAOB | |
| SCHEMBL134086 | 0.80 | IDO1 (0.61) | APPIDO1TSHRMAOB | |
| SCHEMBL2657770 | 0.79 | TSHR (0.71) | APPIDO1TSHRMAOB | |
| SCHEMBL3500426 | 0.79 | TSHR (0.71) | APPIDO1CYP3A4TSHR | |
| SCHEMBL9342149 | 0.78 | IDO1 (0.58) | APPIDO1TSHRMAOB | |
| SCHEMBL8142452 | 0.78 | APP (0.57) | APPIDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758453-B2 | One-component reagent for the fluoroalkylation reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF LLLINOIS (US) | 2016-06-30 | — | — | US | disclosed |
| US-9193648-B2 | Fluoroalkylation methods and reagents | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-24 | — | — | US | disclosed |
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2606048-A1 | FLUOROALKYLATION METHODS AND REAGENTS | The Board of Trustees of the University of Illinois (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024564-A1 | FLUOROALKYLATION METHODS AND REAGENTS | THE BOARD OF TRUSTESS OF THE UNIVERSITY OF ILLINOIS (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225815-A1 | Fluoroalkylation Methods And Reagents | ALK, AFF4, AFF2 | APP 2779/4885IDO1 4246/4885CYP3A4 718/4885 |
| US-20160185691-A1 | One-Component Reagent for the Fluoroalkylation Reaction | AOC1, AOC3, AOC2 | APP 4526/4885IDO1 2884/4885CYP3A4 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.