SCHEMBL18430506

SCHEMBL18430506

COC(=O)NCCCc1cc(OC)cc([C@@H](C)N(C(=O)[C@H]2CNCCO2)C2CC2)c1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18430507 0.91 REN (0.73) REN
SCHEMBL17013613 0.90 REN (0.72) REN
SCHEMBL17013601 0.88 REN (0.71) REN
SCHEMBL17013612 0.87 REN (0.79) REN
SCHEMBL16471595 0.85 REN (0.78) REN
SCHEMBL19512233 0.85 REN (1.00) REN
SCHEMBL16471602 0.85 REN (1.00) REN
SCHEMBL16471605 0.85 REN (1.00) REN
SCHEMBL16471594 0.85 REN (0.78) REN
SCHEMBL17013669 0.85 REN (0.75) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556159-B2 Renin inhibitor MITSUBISHI TANABE PHARMA CORPORATION (JP) 2017-01-31 — — US disclosed
Send feedback