Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | LIPA | P38571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18433460 | 0.90 | PARP1 (0.34) | KDM4ECNR2 | |
| SCHEMBL12544225 | 0.86 | KDM4E (0.33) | KDM4ECNR2PIK3CDCNR1CHRM2 | |
| SCHEMBL12566334 | 0.85 | MAPK1 (0.33) | KDM4ECNR2PIK3CDCNR1MAPK1 | |
| SCHEMBL18433368 | 0.85 | PIK3CD (0.37) | KDM4ECNR2PIK3CDCNR1 | |
| SCHEMBL20683255 | 0.81 | PIK3CD (0.37) | KDM4EPIK3CDTNKS2 | |
| SCHEMBL13227035 | 0.77 | NCF1 (0.38) | KDM4E | |
| SCHEMBL12543521 | 0.77 | PARP1 (0.33) | KDM4E | |
| SCHEMBL5986834 | 0.76 | KDM4E (0.40) | KDM4EPIK3CDTNKS2 | |
| SCHEMBL9278642 | 0.75 | KDM4E (0.34) | KDM4ECNR2PIK3CDCNR1CHRM2 | |
| SCHEMBL13727465 | 0.75 | LIPA (0.42) | CNR2PIK3CDCNR1TNKS2LIPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2716635-B1 | Compounds which selectively modulate the CB2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2017-02-01 | — | — | EP | disclosed |