Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 11/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434842 | 0.81 | SLC40A1 (0.52) | SLC40A1 | |
| SCHEMBL18434791 | 0.81 | SLC40A1 (0.52) | SLC40A1MAPK14 | |
| SCHEMBL11995745 | 0.81 | SLC40A1 (0.60) | SLC40A1 | |
| SCHEMBL18434650 | 0.81 | SLC40A1 (0.55) | SLC40A1 | |
| SCHEMBL18434816 | 0.78 | SLC40A1 (0.55) | SLC40A1 | |
| SCHEMBL18434399 | 0.78 | SLC40A1 (0.57) | SLC40A1 | |
| SCHEMBL18434713 | 0.76 | SLC40A1 (0.60) | SLC40A1 | |
| SCHEMBL11995746 | 0.76 | SLC40A1 (0.60) | SLC40A1 | |
| SCHEMBL18434662 | 0.73 | SLC40A1 (0.58) | SLC40A1MAPK14 | |
| SCHEMBL11973651 | 0.71 | SLC40A1 (1.00) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |