Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093783 | 0.79 | METAP1 (0.37) | METAP1 | |
| SCHEMBL17607481 | 0.72 | METAP1 (0.33) | METAP1 | |
| SCHEMBL23032033 | 0.71 | METAP1 (0.34) | METAP1 | |
| SCHEMBL9438282 | 0.71 | METAP1 (0.36) | METAP1 | |
| SCHEMBL19541435 | 0.70 | METAP1 (0.41) | METAP1 | |
| SCHEMBL17134911 | 0.70 | METAP1 (0.32) | METAP1 | |
| SCHEMBL25533254 | 0.70 | LMNA (0.36) | — | |
| SCHEMBL4653100 | 0.70 | METAP1 (0.39) | METAP1 | |
| SCHEMBL21311370 | 0.70 | ANPEP (0.36) | — | |
| SCHEMBL7391772 | 0.69 | TSHR (0.33) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |