Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21336715 | 0.86 | GPR119 (0.44) | GPR119MAPTLMNAKDM4EGAA | |
| SCHEMBL18436239 | 0.86 | GPR119 (0.44) | GPR119MAPTLMNAKDM4EGAA | |
| SCHEMBL18436372 | 0.86 | MAPT (0.46) | GPR119MAPTLMNAKDM4EGAA | |
| SCHEMBL19012591 | 0.86 | MAPT (0.46) | GPR119MAPTLMNAKDM4EGAA | |
| SCHEMBL19012386 | 0.83 | MAPT (0.43) | MAPTLMNAKDM4EGAAALDH1A1 | |
| SCHEMBL19012520 | 0.83 | MAPT (0.43) | MAPTLMNAKDM4EGAAALDH1A1 | |
| SCHEMBL21336929 | 0.83 | HTR2C (0.49) | MAPTLMNAKDM4EGAAALDH1A1 | |
| SCHEMBL19012457 | 0.81 | GAA (0.44) | MAPTLMNAKDM4EGAAALDH1A1 | |
| SCHEMBL19001086 | 0.81 | CYP2C9 (0.43) | MAPTLMNAKDM4EGAAHRH2 | |
| SCHEMBL19001144 | 0.81 | CYP2C9 (0.43) | MAPTLMNAKDM4EGAAHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |