SCHEMBL18436365

SCHEMBL18436365

C/C(=C\CCCC=O)CCCC(C)(C)O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
HPGD P15428 1/20 0.38
ALOX15 P16050 2/20 0.37
HIF1A Q16665 1/20 0.36
KDM1A O60341 1/20 0.35
SQLE Q14534 3/20 0.34
ELANE P08246 3/20 0.33
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16294982 0.91 SQLE (0.39) CYP1A1CYP1B1HPGDALOX15KDM1A
SCHEMBL16296254 0.91 SQLE (0.39) CYP1A1CYP1B1HPGDALOX15KDM1A
SCHEMBL21986504 0.91 SQLE (0.39) CYP1A1CYP1B1HPGDALOX15KDM1A
SCHEMBL16671129 0.79 SQLE (0.46) CYP1A1CYP1B1ALOX15KDM1ASQLE
SCHEMBL16671131 0.79 SQLE (0.46) CYP1A1CYP1B1ALOX15KDM1ASQLE
SCHEMBL27509626 0.78
SCHEMBL18116630 0.78 ALOX15 (0.46) CYP1A1CYP1B1ALOX15KDM1ASQLE
SCHEMBL18686407 0.76 KMT2A (0.63) ALOX15SQLEKMT2A
SCHEMBL17208654 0.76 ALOX15 (0.45) CYP1A1CYP1B1ALOX15KDM1ASQLE
SCHEMBL17240273 0.76 KDM1A (0.58) HPGDHIF1AKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2920139-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2017-02-01 EP disclosed