Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843216 | 0.87 | GAA (0.68) | GAAMAPK1SMN1; SMN2HPGDRECQL | |
| SCHEMBL1843219 | 0.87 | GAA (0.68) | GAAMAPK1SMN1; SMN2HPGDRECQL | |
| SCHEMBL30240785 | 0.87 | GAA (0.68) | GAAMAPK1SMN1; SMN2HPGDRECQL | |
| SCHEMBL5705557 | 0.87 | GAA (0.68) | GAAMAPK1SMN1; SMN2HPGDRECQL | |
| SCHEMBL1842720 | 0.83 | MEN1 (0.60) | GAAMAPK1SMN1; SMN2RECQLNPC1 | |
| SCHEMBL2282341 | 0.79 | TP53 (0.52) | GAASMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL1563698 | 0.77 | GAA (0.67) | GAAMAPK1SMN1; SMN2HPGDRECQL | |
| SCHEMBL21433610 | 0.77 | GAA (0.55) | GAAMAPK1SMN1; SMN2HPGDRECQL | |
| SCHEMBL21433611 | 0.77 | GAA (0.55) | GAAMAPK1SMN1; SMN2HPGDRECQL | |
| SCHEMBL23701490 | 0.76 | KDM1A (0.74) | GAAMAPK1SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2954001-B1 | TYRE HIGH-STIFFNESS COMPOUND | BRIDGESTONE CORP (JP) | 2017-01-04 | — | — | EP | claimed |
| US-20150368445-A1 | TYRE HIGH-STIFFNESS COMPOUND | BRIDGESTONE CORPORATION (JP) | 2015-12-24 | — | — | US | claimed |
| EP-2954001-A1 | TYRE HIGH-STIFFNESS COMPOUND | Bridgestone Corporation (JP) | 2015-12-16 | — | — | EP | claimed |
| WO-2014122623-A1 | TYRE HIGH-STIFFNESS COMPOUND | BRIDGESTONE CORPORATION (JP) | 2014-08-14 | — | — | WO | claimed |
| EP-1083199-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2006-08-02 | — | — | EP | claimed |
| EP-1184412-B1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | BRIDGESTONE CORP (JP) | 2005-01-12 | — | — | EP | claimed |
| US-6822027-B2 | MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. | BRIDGESTONE CORPORATION (JP) | 2004-11-23 | — | — | US | claimed |
| US-6506849-B1 | Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity | BRIDGESTONE CORPORATION (JP) | 2003-01-14 | — | — | US | claimed |
| US-9593231-B2 | Tire | BRIDGESTONE CORPORATION (JP) | 2017-03-14 | — | — | US | disclosed |
| US-9556351-B2 | Rubber composition suitable for use as a cap ply in a tire | Bridgestone Americas Tire Operations, Inc. (US) | 2017-01-31 | — | — | US | disclosed |
| EP-2954001-B1 | TYRE HIGH-STIFFNESS COMPOUND | BRIDGESTONE CORP (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20160040024-A1 | RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC | 2016-02-11 | — | — | US | disclosed |
| US-20150368445-A1 | TYRE HIGH-STIFFNESS COMPOUND | BRIDGESTONE CORPORATION (JP) | 2015-12-24 | — | — | US | disclosed |
| EP-2954001-A1 | TYRE HIGH-STIFFNESS COMPOUND | Bridgestone Corporation (JP) | 2015-12-16 | — | — | EP | disclosed |
| US-6566449-B2 | Obtained from polymerized maleic acid and citraconic acid with methylene polyaniline; elasticity; performance | BRIDGESTONE CORPORATION (JP) | 2003-05-20 | — | — | US | disclosed |
| US-6506849-B1 | Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity | BRIDGESTONE CORPORATION (JP) | 2003-01-14 | — | — | US | disclosed |
| US-20020077423-A1 | Polymaleimide-containing rubber composition and tire | BRIDGESTONE CORPORATION | 2002-06-20 | — | — | US | disclosed |
| US-20020049294-A1 | Rubber composition and heavy duty pneumatic tire using the rubber composition | BRIDGESTONE CORPORATION | 2002-04-25 | — | — | US | disclosed |
| EP-1199331-A1 | Polymaleimide-containing rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2002-04-24 | — | — | EP | disclosed |
| EP-1184412-A1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | Bridgestone Corporation (JP) | 2002-03-06 | — | — | EP | disclosed |