SCHEMBL1843216

SCHEMBL1843216

C/C(CC(C)C)=N/NC(=O)c1ccccc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 9/20 0.68
▸ SMN1; SMN2 Q16637 5/20 0.68
▸ RAB9A P51151 4/20 0.56
▸ HPGD P15428 3/20 0.54
▸ RECQL P46063 1/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ NPC1 O15118 4/20 0.52
▸ KDM4E B2RXH2 3/20 0.52
▸ MAPT P10636 2/20 0.52
▸ LMNA P02545 2/20 0.52
▸ THRB P10828 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ NPSR1 Q6W5P4 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ PKM P14618 1/20 0.52
▸ CTDSP1 Q9GZU7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30240785 1.00 GAA (0.68) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL5705557 1.00 GAA (0.68) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL1843219 1.00 GAA (0.68) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL21433610 0.90 GAA (0.55) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL21433611 0.90 GAA (0.55) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL1843932 0.87 GAA (0.62) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL23485552 0.85 KDM4E (0.50) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL22540076 0.85 KDM4E (0.50) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL5705600 0.84 RAB9A (0.54) GAASMN1; SMN2RAB9AHPGDRECQL
SCHEMBL5705602 0.84 RAB9A (0.54) GAASMN1; SMN2RAB9AHPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 — — EP claimed
EP-2954001-B1 TYRE HIGH-STIFFNESS COMPOUND BRIDGESTONE CORP (JP) 2017-01-04 — — EP claimed
US-20150368445-A1 TYRE HIGH-STIFFNESS COMPOUND BRIDGESTONE CORPORATION (JP) 2015-12-24 — — US claimed
EP-2954001-A1 TYRE HIGH-STIFFNESS COMPOUND Bridgestone Corporation (JP) 2015-12-16 — — EP claimed
WO-2014122623-A1 TYRE HIGH-STIFFNESS COMPOUND BRIDGESTONE CORPORATION (JP) 2014-08-14 — — WO claimed
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 — — EP claimed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 — — EP claimed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 — — US claimed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 — — US claimed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 — — EP disclosed
US-11306201-B2 Rubber composition for tires and tire BRIDGESTONE CORPORATION (JP) 2022-04-19 — — US disclosed
EP-3725838-A1 RUBBER COMPOSITION FOR TIRE TREAD AND TIRE Bridgestone Corporation (JP) 2020-10-21 — — EP disclosed
US-20200299490-A1 RUBBER COMPOSITION FOR TIRE TREAD AND TIRE BRIDGESTONE CORPORATION (JP) 2020-09-24 — — US disclosed
US-20200283613-A1 RUBBER COMPOSITION FOR TIRES AND TIRE BRIDGESTONE CORPORATION (JP) 2020-09-10 — — US disclosed
US-6566449-B2 Obtained from polymerized maleic acid and citraconic acid with methylene polyaniline; elasticity; performance BRIDGESTONE CORPORATION (JP) 2003-05-20 — — US disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 — — US disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 — — US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 — — US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 — — EP disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 — — EP disclosed
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