⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844004 | 1.00 | — | — | |
| SCHEMBL1846403 | 1.00 | — | — | |
| SCHEMBL9648798 | 0.72 | — | — | |
| SCHEMBL1100301 | 0.71 | MAPT (0.31) | — | |
| SCHEMBL10515729 | 0.70 | — | — | |
| SCHEMBL18920313 | 0.67 | — | — | |
| SCHEMBL10870478 | 0.66 | — | — | |
| SCHEMBL4587470 | 0.64 | ALDH1A1 (0.35) | — | |
| SCHEMBL28453437 | 0.62 | — | — | |
| SCHEMBL7493967 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023631-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-02-09 | — | — | WO | disclosed |
| US-20130345432-A1 | ASYMMETRIC PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES | AMGEN INC. (US) | 2013-12-26 | — | — | US | disclosed |
| US-8501954-B2 | Asymmetric process for making substituted 2-amino-thiazolones | AMGEN INC. (US) | 2013-08-06 | — | — | US | disclosed |
| EP-2321290-B1 | ASYMMETRIC PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES | AMGEN INC (US) | 2012-06-20 | — | — | EP | disclosed |
| US-20110178307-A1 | ASYMMETRIC PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES | AMGEN INC. (US) | 2011-07-21 | — | — | US | disclosed |
| EP-2321290-A1 | ASYMMETRIC PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES | Amgen, Inc (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010014586-A1 | ASYMMETRIC PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES | AMGEN INC. (US) | 2010-02-04 | — | — | WO | disclosed |