Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061274 | 0.87 | MAPT (0.54) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| Water SCHEMBL9652876 | 0.83 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL31365177 | 0.82 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8749218 | 0.82 | KMT2A (0.62) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL18395639 | 0.81 | MAPT (0.56) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL5982382 | 0.81 | KAT2B (0.64) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL5671580 | 0.81 | MAPT (0.58) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL9311420 | 0.81 | CXCR2 (0.59) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL3824748 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL11507416 | 0.81 | APP (0.57) | MAPTSMN1; SMN2LMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496558-A1 | MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED ALKALISING AGENT | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | disclosed |
| EP-4288028-A1 | METHOD FOR TREATING HUMAN HAIR WITH AGENTS CONTAINING MIXTURES OF ORGANIC C1-C6-ALKOXY-SILOXANES | Henkel AG & Co. KGaA (DE) | 2023-12-13 | — | — | EP | disclosed |
| WO-2023179921-A1 | MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED ALKALISING AGENT | HENKEL AG & CO. KGAA (DE) | 2023-09-28 | — | — | WO | disclosed |
| EP-4149411-A1 | METHOD FOR TREATING HUMAN HAIR WITH AGENTS CONTAINING MIXTURES OF ORGANIC C1-C6 ALKOXY SILOXANES | Henkel AG & Co. KGaA (DE) | 2023-03-22 | — | — | EP | disclosed |
| WO-2022167184-A1 | METHOD FOR TREATING HUMAN HAIR WITH AGENTS CONTAINING MIXTURES OF ORGANIC C1-C6 ALKOXY SILOXANES | HENKEL AG & CO. KGAA (DE) | 2022-08-11 | — | — | WO | disclosed |
| EP-4007558-A1 | METHOD FOR TREATING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY-SILANE AND AN AMINO ACID AND/OR AMINO ACID DERIVATIVE | Henkel AG & Co. KGaA (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-2684874-B1 | Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and C-met inhibitors | CEPHALON INC (US) | 2017-05-17 | — | — | EP | disclosed |
| EP-2222647-B1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON INC (US) | 2015-08-05 | — | — | EP | disclosed |
| EP-2791252-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2014-10-22 | — | — | EP | disclosed |
| EP-2684874-A1 | Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and C-met inhibitors | Cephalon, Inc. (US) | 2014-01-15 | — | — | EP | disclosed |
| EP-2320854-A2 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2011-05-18 | — | — | EP | disclosed |
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2010066721-A2 | TONICIZING COLORATION | HENKEL AG & CO. KGAA (DE) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010029006-A2 | BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | WO | disclosed |
| CN-101535276-A | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-09-16 | — | — | CN | disclosed |
| US-20090221555-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND c-MET INHIBITORS | CEPHALON, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| EP-1727513-A1 | HAIR COLORING AGENT CONTAINING INDIGOID VAT DYES | Wella Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005094763-A1 | HAIR COLORING AGENT CONTAINING INDIGOID VAT DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2005-10-13 | — | — | WO | disclosed |
| EP-0376047-A1 | 2-Amino-6-chloro-4-nitrophenol derivatives, process for their preparation and hair dyeing agent containing the same | Wella Aktiengesellschaft (DE) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221555-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND c-MET INHIBITORS | ALK, MET, RET | MAPT 3881/4885SMN1; SMN2 2836/4885LMNA 3814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.