⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070023 | 0.84 | — | — | |
| SCHEMBL23965539 | 0.75 | — | — | |
| SCHEMBL26236 | 0.75 | — | — | |
| SCHEMBL13283251 | 0.75 | ADH1B (0.68) | — | |
| SCHEMBL19281716 | 0.74 | TAAR1 (0.35) | — | |
| SCHEMBL17928056 | 0.73 | ADH1B (0.52) | — | |
| SCHEMBL19390046 | 0.72 | — | — | |
| SCHEMBL15172204 | 0.72 | ADH1B (0.64) | — | |
| SCHEMBL13351298 | 0.72 | — | — | |
| SCHEMBL20626902 | 0.72 | ADH1B (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540358-B2 | Tricyclic compounds as anticancer agents | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2017-01-10 | — | — | US | disclosed |
| US-9243077-B2 | Derivative of hyaluronic acid modified with amino-carboxylic acid | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-01-26 | — | — | US | disclosed |
| US-20140213578-A1 | TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS | MT. SINAI SCHOOL OF MEDICINE (US) | 2014-07-31 | — | — | US | disclosed |
| US-8071640-B2 | Urea oligomers, their preparation process and pharmaceutical compositions containing them | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-12-06 | — | — | US | disclosed |
| EP-2323144-A1 | Electrolytic capacitor | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-05-18 | — | — | EP | disclosed |
| US-20100184849-A1 | UREA OLIGOMERS, THEIR PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQU (FR) | 2010-07-22 | — | — | US | disclosed |
| US-7691899-B2 | Urea oligomers, the preparation method thereof and pharmaceutical composition containing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-04-06 | — | — | US | disclosed |
| EP-1020446-B1 | NAPHTHALIMIDOBENZAMIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2006-03-15 | — | — | EP | disclosed |
| US-6300331-B1 | DRUGS AS ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1020446-A1 | NAPHTHALIMIDOBENZAMIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |