SCHEMBL184485

SCHEMBL184485

O=C(O)c1ccc(O)c(Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.68
CA2 P00918 5/20 0.64
CA1 P00915 4/20 0.64
MAPT P10636 2/20 0.64
CA12 O43570 2/20 0.64
CA4 P22748 2/20 0.64
CA6 P23280 2/20 0.64
CA7 P43166 2/20 0.64
CA9 Q16790 2/20 0.64
CA14 Q9ULX7 2/20 0.64
KDM4E B2RXH2 1/20 0.64
POLB P06746 1/20 0.64
GAA P10253 1/20 0.64
PTGS2 P35354 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
TTR P02766 2/20 0.58
HSP90AA1 P07900 1/20 0.55
HSP90AB1 P08238 1/20 0.55
SRD5A2 P31213 1/20 0.53
HSD17B10 Q99714 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29524547 1.00 TSHR (0.68) TSHRCA2CA1MAPTCA12
SCHEMBL2649150 1.00 TSHR (0.68) TSHRCA2CA1MAPTCA12
Water SCHEMBL1984245 0.98 TSHR (0.65) TSHRCA2CA1MAPTCA12
Water SCHEMBL1984247 0.98 TSHR (0.65) TSHRCA2CA1MAPTCA12
Hydrochloric Acid SCHEMBL11158583 0.98 TSHR (0.65) TSHRCA2CA1MAPTCA12
Hydrazine SCHEMBL27542387 0.96 TSHR (0.63) TSHRCA2CA1MAPTCA12
Cyclohexane SCHEMBL1356517 0.94 TSHR (0.61) TSHRCA2CA1MAPTCA12
Paraben SCHEMBL27501871 0.92 CA2 (0.61) TSHRCA2CA1MAPTCA12
Biphenyl SCHEMBL27517102 0.90 ESR2 (0.63) TSHRCA2CA1MAPTCA12
SCHEMBL2649763 0.89 KDM4E (0.59) TSHRCA2CA1MAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118549570-A Detection method of 13 disinfection byproducts in sediment 上海市环境科学研究院 2024-08-27 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117843749-B Solid phase synthesis method of arginine/lysine polypeptide 成都圣诺生物多肽科技有限公司 2024-05-28 CN claimed
CN-113651786-B Method for synthesizing 6-hydroxy-2-ethyl-2H-pyrone- [3] by catalyzing oxidation of alpha-furopropanol and product thereof 上海万香日化有限公司 2024-04-23 CN claimed
CN-117843749-A Solid phase synthesis method of arginine/lysine polypeptide 成都圣诺生物多肽科技有限公司 2024-04-09 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
EP-3569248-B1 GIP INHIBITORS FOR IMPROVING COGNITIVE FUNCTION KAO CORP (JP) 2023-12-06 EP claimed
EP-3560515-B1 GIP INHIBITORS FOR USE IN IMPROVING MOTOR CONTROL FUNCTION KAO CORP (JP) 2023-11-15 EP claimed
CN-114671753-A Synthetic method of 3-chloro-4-hydroxybenzoic acid 营口兴福化工有限公司 2022-06-28 CN claimed
CN-114113370-A Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2022-03-01 CN claimed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP claimed
EP-0323710-A1 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-12 EP claimed
EP-0321107-A1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-21 EP claimed
US-4782132-A Process for producing a copolyester MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1988-11-01 US claimed
US-4737398-A POLYAZOMETHYNE, POLYESTER OR POLYCARBONATE POLYPLASTICS CO., LTD. (JP) 1988-04-12 US claimed
US-4726998-A LIQUID CRYSTAL POLYMER SUBSTRATE, MAGNETIC LAYER POLYPLASTICS CO., LTD. (JP) 1988-02-23 US claimed
EP-0134959-B1 THERMOTROPIC AROMATIC POLYESTERS HAVING A HIGH RIGIDITY AND RESILIENCY, PROCESS FOR THEIR USE IN THE PRODUCTION OF MOULDED ARTICLES, FILAMENTS, FIBRES AND SHEETS BAYER AG (DE) 1986-12-30 EP claimed
US-4536561-A RIGID, TOUGH MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US claimed
EP-0134959-A1 Thermotropic aromatic polyesters having a high rigidity and resiliency, process for their use in the production of moulded articles, filaments, fibres and sheets BAYER AG (DE) 1985-03-27 EP claimed
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US claimed