Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222134 | 0.76 | GAA (0.38) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL5667071 | 0.75 | CA12 (0.38) | GAAKMT2AMEN1NPC1RAB9A | |
| Acetone SCHEMBL4249268 | 0.74 | CA12 (0.36) | GAAKMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7268096 | 0.74 | CA12 (0.37) | GAAKMT2AMEN1RAB9AALDH1A1 | |
| Acetone SCHEMBL20164099 | 0.73 | CA12 (0.35) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL1845186 | 0.73 | CA12 (0.31) | CA12CA1CA9 | |
| SCHEMBL1509167 | 0.68 | GAA (0.41) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29057093 | 0.68 | ATR (0.36) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL19024360 | 0.67 | GAA (0.47) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8190552 | 0.66 | NPC1 (0.60) | GAAKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9861713-B2 | PSMA-binding agents and uses thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-01-09 | — | — | US | disclosed |
| US-20160114060-A1 | PSMA-BINDING AGENTS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-04-28 | — | — | US | disclosed |
| EP-0862464-B1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | UNIV EMORY (US) | 2012-08-22 | — | — | EP | disclosed |
| EP-2324857-A1 | Imaging agents for early detection of cardiovascular plaque | The General Hospital Corporation (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20090117032-A1 | Imaging Agents for Early Detection and Monitoring of Cardiovascular Plaque | THE GENERAL HOSPITAL CORPORATION (US) | 2009-05-07 | — | — | US | disclosed |
| US-7438891-B2 | Imaging agents for early detection and monitoring of cardiovascular plaque | THE GENERAL HOSPITAL CORPORATION | 2008-10-21 | — | — | US | disclosed |
| US-20060140859-A1 | Imaging agents for early detection and monitoring of cardiovascular plaque | MASSACHUSETTS GENERAL HOSPITAL (US) | 2006-06-29 | — | — | US | disclosed |
| US-7060251-B1 | Imaging agents for early detection and monitoring of cardiovascular plaque | THE GENERAL HOSPITAL CORPORATION (US) | 2006-06-13 | — | — | US | disclosed |
| EP-0862464-A4 | AMINO ACID ANALOGS FOR TUMOR IMAGING | UNIV EMORY (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-1011738-A1 | IMAGING AGENTS FOR EARLY DETECTION OF CARDIOVASCULAR PLAQUE | THE GENERAL HOSPITAL CORPORATION (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999012579-A1 | IMAGING AGENTS FOR EARLY DETECTION AND MONITORING OF CARDIOVASCULAR PLAQUE | THE GENERAL HOSPITAL CORPORATION (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5817776-A | TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY | EMORY UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0862464-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114060-A1 | PSMA-BINDING AGENTS AND USES THEREOF | KLK3, FOLH1, DNPEP | GAA 197/4885KMT2A 220/4885MEN1 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.