Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845191 | 0.73 | GAA (0.42) | CA12CA1CA9 | |
| SCHEMBL19583659 | 0.70 | KDM4E (0.31) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1509166 | 0.67 | CRBN (0.36) | — | |
| SCHEMBL5667071 | 0.67 | CA12 (0.38) | CA12CA1CA9GABRPGABRD | |
| Acetone SCHEMBL4249268 | 0.67 | CA12 (0.36) | CA12CA1CA9GABRPGABRD | |
| SCHEMBL2558802 | 0.66 | HCAR3 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL7268096 | 0.66 | CA12 (0.37) | CA12CA1CA9GABRPGABRD | |
| Acetone SCHEMBL20164099 | 0.66 | CA12 (0.35) | CA12CA1CA9GABRPGABRD | |
| SCHEMBL7907251 | 0.64 | NPSR1 (0.35) | — | |
| SCHEMBL1690946 | 0.64 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862464-B1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | UNIV EMORY (US) | 2012-08-22 | — | — | EP | disclosed |
| EP-2324857-A1 | Imaging agents for early detection of cardiovascular plaque | The General Hospital Corporation (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20090117032-A1 | Imaging Agents for Early Detection and Monitoring of Cardiovascular Plaque | THE GENERAL HOSPITAL CORPORATION (US) | 2009-05-07 | — | — | US | disclosed |
| US-7438891-B2 | Imaging agents for early detection and monitoring of cardiovascular plaque | THE GENERAL HOSPITAL CORPORATION | 2008-10-21 | — | — | US | disclosed |
| US-20060140859-A1 | Imaging agents for early detection and monitoring of cardiovascular plaque | MASSACHUSETTS GENERAL HOSPITAL (US) | 2006-06-29 | — | — | US | disclosed |
| US-7060251-B1 | Imaging agents for early detection and monitoring of cardiovascular plaque | THE GENERAL HOSPITAL CORPORATION (US) | 2006-06-13 | — | — | US | disclosed |
| EP-0862464-A4 | AMINO ACID ANALOGS FOR TUMOR IMAGING | UNIV EMORY (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-1011738-A1 | IMAGING AGENTS FOR EARLY DETECTION OF CARDIOVASCULAR PLAQUE | THE GENERAL HOSPITAL CORPORATION (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999012579-A1 | IMAGING AGENTS FOR EARLY DETECTION AND MONITORING OF CARDIOVASCULAR PLAQUE | THE GENERAL HOSPITAL CORPORATION (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5817776-A | TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY | EMORY UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0862464-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |