Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NR5A2 | O00482 | 2/20 | 0.57 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021533 | 0.93 | SMN1; SMN2 (0.66) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL327161 | 0.93 | SMN1; SMN2 (0.66) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL3502856 | 0.93 | SMN1; SMN2 (0.66) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL160176 | 0.91 | SMN1; SMN2 (0.63) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL747961 | 0.87 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL672430 | 0.87 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL326877 | 0.87 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL326926 | 0.87 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL5698359 | 0.87 | SMN1; SMN2 (0.74) | SMN1; SMN2NR5A2NR5A1ALDH1A1FABP3 | |
| SCHEMBL18628315 | 0.84 | S1PR1 (0.61) | SMN1; SMN2NR5A2NR5A1ALDH1A1SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150196589-A1 | FORMULATIONS FOR ALTERATION OF BIOPHYSICAL PROPERTIES OF MUCOSAL LINING | PULMATRIX, INC. | 2015-07-16 | — | — | US | disclosed |
| EP-2402001-A1 | Formulations for alteration of biophysical properties of mucosal lining | Pulmatrix, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |
| EP-2308469-A1 | Formulations for alteration of biophysical properties of mucosal lining | Pulmatrix, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010103514-A1 | SILICA NANOCAPSULES FROM NANO-EMULSIONS OBTAINED BY PHASE INVERSION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-09-16 | — | — | WO | disclosed |
| EP-1906922-A2 | FORMULATIONS FOR ALTERATION OF BIOPHYSICAL PROPERTIES OF MUCOSAL LINING | Pulmatrix, Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20080038207-A1 | Method and device for decreasing contamination | PULMATRIX, INC. | 2008-02-14 | — | — | US | disclosed |
| US-20070053844-A1 | FORMULATIONS FOR ALTERATION OF BIOPHYSICAL PROPERTIES OF MUCOSAL LINING | PULMATRIX INC. | 2007-03-08 | — | — | US | disclosed |
| WO-2006125153-A2 | FORMULATIONS FOR ALTERATION OF BIOPHYSICAL PROPERTIES OF MUCOSAL LINING | PULMATRIX INC. (US) | 2006-11-23 | — | — | WO | disclosed |