SCHEMBL672430

SCHEMBL672430

CCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OC(CC)C[N+](C)(C)C)OC(=O)CCCCCCCCCCCCC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.74
NR5A2 O00482 1/20 0.74
NR5A1 Q13285 1/20 0.74
FABP3 P05413 1/20 0.66
MAPT P10636 2/20 0.65
LPAR3 Q9UBY5 7/20 0.61
LPAR1 Q92633 4/20 0.61
ENPP2 Q13822 3/20 0.61
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
RECQL P46063 1/20 0.57
LPAR2 Q9HBW0 2/20 0.57
TP53 P04637 2/20 0.53
CYP2D6 P10635 2/20 0.53
TSHR P16473 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
NFKB1 P19838 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL326926 1.00 SMN1; SMN2 (0.74) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL326877 1.00 SMN1; SMN2 (0.74) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL747961 1.00 SMN1; SMN2 (0.74) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL5698359 1.00 SMN1; SMN2 (0.74) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL327161 0.94 SMN1; SMN2 (0.66) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL2021533 0.94 SMN1; SMN2 (0.66) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL3502856 0.94 SMN1; SMN2 (0.66) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL160176 0.92 SMN1; SMN2 (0.63) SMN1; SMN2NR5A2NR5A1FABP3MAPT
SCHEMBL6265990 0.90 SMN1; SMN2 (0.60) SMN1; SMN2NR5A2NR5A1FABP3MAPT
Hydrochloric Acid SCHEMBL15093812 0.88 FABP3 (0.70) SMN1; SMN2NR5A2NR5A1FABP3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024144348-A1 VACCINE COMPOSITION COMPRISING IONIC COMPLEX OF CATIONIC MOLECULAR TRANSPORTER AND MRNA 주식회사 바이오파마 2024-07-04 WO claimed
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. 2024-07-04 US claimed
WO-2024128719-A1 METHOD FOR DETECTING HIGH SENSITIVITY OF CANCER CELL-DERIVED EXTRACELLULAR VESICLE GENE BY USING FUSION REACTION WITH LIPOSOMES 기초과학연구원 2024-06-20 WO claimed
WO-2024123633-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF RECODE THERAPEUTICS, INC. (US) 2024-06-13 WO claimed
WO-2024119074-A1 STEALTH LIPID NANOPARTICLE COMPOSITIONS FOR CELL TARGETING GENERATION BIO CO. (US) 2024-06-06 WO claimed
WO-2024119017-A1 SYNTHETIC SINGLE STRANDED NUCLEIC ACID COMPOSITIONS AND METHODS THEREOF GENERATION BIO CO. (US) 2024-06-06 WO claimed
CN-118139613-A Cationic liposome for binding and stabilizing RNA, application thereof and method for loading of canamycin on liposome BS生物技术股份公司 2024-06-04 CN claimed
US-20240165222-A1 VACCINE COMPOSITION FOR PREVENTING SARS-COV-2 EYEGENE INC. (KR) 2024-05-23 US claimed
US-20240148897-A1 COMPOSITION FOR IN VIVO DELIVERY OF RNA AND PREPERATION METHOD THEREFOR EYEGENE INC. (KR) 2024-05-09 US claimed
EP-4356933-A1 COMPOSITION FOR DELIVERING MODIFIED NUCLEIC ACID-CONTAINING MRNA Eyegene, Inc. (KR) 2024-04-24 EP claimed
WO-2016118697-A1 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS PHASERX, INC. (US) 2016-07-28 WO claimed
WO-2015043613-A1 PARTICLES COMPRISING A SHELL WITH RNA BIONTECH AG (DE) 2015-04-02 WO claimed
EP-2654779-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF Ludwig Institute for Cancer Research, Ltd. (US) 2013-10-30 EP claimed
WO-2012088414-A1 LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) 2012-06-28 WO claimed
US-20110160282-A1 NUCLEIC-ACID PHARMACEUTICAL COMPOSITION FOR CANCER THERAPY KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2011-06-30 US claimed
US-7745419-B2 Pharmaceutical composition for treating cancer KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION (KR) 2010-06-29 US claimed
WO-2009104896-A2 NUCLEIC-ACID PHARMACEUTICAL COMPOSITION FOR CANCER THERAPY 고려대학교 산학협력단 (KR) 2009-08-27 WO claimed
US-20090081282-A1 PHARMACEUTICAL COMPOSITION FOR TREATING CANCER KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION (KR) 2009-03-26 US claimed
EP-0819758-B1 Cationic vehicle: DNA complexes and their use in gene therapy MIXSON ARCHIBALD JAMES (US) 2006-09-20 EP claimed
EP-0831923-B1 SEPARATION OF ACTIVE COMPLEXES UNIV CALIFORNIA (US) 2006-07-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165222-A1 VACCINE COMPOSITION FOR PREVENTING SARS-COV-2 ACE2, SARS1, RBM22 SMN1; SMN2 480/4885NR5A2 2098/4885NR5A1 3502/4885
US-20240216290-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, NPC1L1, NPC1 SMN1; SMN2 240/4885NR5A2 3268/4885NR5A1 2323/4885
US-20240148897-A1 COMPOSITION FOR IN VIVO DELIVERY OF RNA AND PREPERATION METHOD THEREFOR RTCB, RRP1B, PRPF6 SMN1; SMN2 817/4885NR5A2 4748/4885NR5A1 3917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.