Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | TACR2 | P21452 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456611 | 1.00 | NAAA (0.46) | NAAAPDPK1MTORTACR2IDO1 | |
| SCHEMBL18349644 | 0.85 | NAAA (0.43) | NAAAPDPK1MTORTACR2PLA2G6 | |
| SCHEMBL18080620 | 0.85 | NAAA (0.43) | NAAAPDPK1MTORTACR2IDO1 | |
| SCHEMBL16805385 | 0.85 | NAAA (0.43) | NAAAPDPK1MTORTACR2IDO1 | |
| SCHEMBL24465178 | 0.84 | BCHE (0.48) | PDPK1MTORTACR2SLC6A2CTRB1 | |
| SCHEMBL147364 | 0.84 | BCHE (0.45) | NAAAPDPK1MTORTACR2IDO1 | |
| SCHEMBL18797793 | 0.84 | BCHE (0.48) | PDPK1MTORTACR2SLC6A2CTRB1 | |
| SCHEMBL18815483 | 0.84 | BCHE (0.48) | PDPK1MTORTACR2SLC6A2CTRB1 | |
| SCHEMBL18817807 | 0.84 | BCHE (0.48) | PDPK1MTORTACR2SLC6A2CTRB1 | |
| SCHEMBL18522464 | 0.82 | NAAA (0.41) | NAAAPDPK1MTORTACR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328832-B1 | FUCOSIDASE INHIBITORS | HORIZON ORPHAN LLC (US) | 2021-03-03 | — | — | EP | disclosed |
| WO-2017019925-A1 | FUCOSIDASE INHIBITORS | RAPTOR PHARMACEUTICALS INC. (US) | 2017-02-02 | — | — | WO | disclosed |