Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 7/20 | 1.00 |
| ▸ | PTGDR | Q13258 | 6/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | DRD1 | P21728 | 1/20 | 0.83 |
| ▸ | CCKAR | P32238 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16558830 | 1.00 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9879982 | 0.92 | PTGDR2 (0.85) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL29031 | 0.91 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL20769768 | 0.91 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL1427851 | 0.91 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL29030 | 0.91 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL29503087 | 0.91 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL19799335 | 0.90 | PTGDR2 (0.82) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL698600 | 0.90 | PTGDR2 (0.82) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL1427848 | 0.90 | PTGDR2 (0.98) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017019858-A1 | SINGLE NUCLEOTIDE POLYMORPHIC ALLELES OF HUMAN DP-2 GENE FOR DETECTION OF SUSCEPTIBILITY TO HAIR GROWTH INHIBITION BY PGD2 | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-02-02 | — | — | WO | disclosed |