Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.85 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.85 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | DRD1 | P21728 | 1/20 | 0.70 |
| ▸ | CCKAR | P32238 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456875 | 0.92 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL698600 | 0.92 | PTGDR2 (0.82) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL16558830 | 0.92 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL19799335 | 0.92 | PTGDR2 (0.82) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL3021349 | 0.90 | PTGDR2 (0.78) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9833660 | 0.89 | PTGDR2 (0.87) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL833260 | 0.88 | PTGDR2 (0.70) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL833502 | 0.88 | PTGDR2 (0.70) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL833259 | 0.88 | PTGDR2 (0.70) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL1427848 | 0.84 | PTGDR2 (0.98) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988820-A | Inhibiting platelet aggregation, anticoagulants, thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4965258-A | Anticoagulant; thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4904797-A | REACTING A (BENZENESULFONAMIDOALKYL)CYCLOALKANO(1,2-B)INDOLE WITH ACRYLONITRILE; HYDROLYSIS, HYDROGENATION, REDUCTION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |