Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660811 | 0.90 | LMNA (0.41) | LMNAPTPN1CA1KDM1AMEN1 | |
| SCHEMBL7738221 | 0.86 | LMNA (0.39) | LMNAPTPN1MEN1ALOX15KMT2A | |
| SCHEMBL18896455 | 0.85 | CA1 (0.39) | CA1 | |
| SCHEMBL7744143 | 0.85 | LMNA (0.46) | LMNAPTPN1MEN1CYP3A4ALOX15 | |
| SCHEMBL11692425 | 0.83 | LMNA (0.36) | LMNAPTPN1CA1KDM1AMEN1 | |
| SCHEMBL7743686 | 0.82 | FFAR4 (0.42) | LMNAMEN1KMT2A | |
| SCHEMBL7743492 | 0.82 | FFAR4 (0.42) | LMNAMEN1KMT2A | |
| SCHEMBL7743769 | 0.82 | FFAR4 (0.42) | LMNAMEN1KMT2A | |
| SCHEMBL11636868 | 0.81 | PTPN1 (0.38) | LMNAPTPN1CA1KDM1AMEN1 | |
| SCHEMBL8218123 | 0.81 | LMNA (0.35) | LMNAPTPN1CA1KDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017019175-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | NEWLINK GENETICS CORPORATION (US) | 2017-02-02 | — | — | WO | disclosed |