SCHEMBL18458902

SCHEMBL18458902

CCC(N)C1CCC(C2CCC(c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 12/20 0.34
DPP9 Q86TI2 8/20 0.34
DPP7 Q9UHL4 7/20 0.34
DPP8 Q6V1X1 5/20 0.34
APP P05067 2/20 0.34
FASN P49327 1/20 0.34
CYP3A4 P08684 3/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458840 0.96 APP (0.36) DPP4DPP9DPP7DPP8APP
SCHEMBL19646103 0.93 DPP4 (0.33) DPP4DPP9DPP7DPP8APP
SCHEMBL18458722 0.88 DPP4 (0.36) DPP4DPP9DPP7DPP8APP
SCHEMBL18458615 0.87 DPP4 (0.38) DPP4DPP9DPP7DPP8
SCHEMBL18458837 0.86 DPP4 (0.40) DPP4DPP9DPP7DPP8
SCHEMBL20160836 0.86 DPP4 (0.40) DPP4DPP9DPP7DPP8
SCHEMBL18392484 0.85 CYP3A4 (0.36) APPFASNCYP3A4CYP2C9CYP2D6
SCHEMBL19619448 0.85 APP (0.38) DPP4DPP9DPP7DPP8APP
SCHEMBL19097978 0.85 FEN1 (0.34) APPFASN
SCHEMBL18458593 0.84 APP (0.41) DPP4DPP9DPP7DPP8APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
EP-3450523-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DAINIPPON INK & CHEMICALS (JP) 2021-01-06 EP disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
US-10414979-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-17 US disclosed
US-10400168-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-03 US disclosed
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-10208250-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-02-19 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
EP-2883938-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DAINIPPON INK & CHEMICALS (JP) 2017-10-25 EP disclosed
US-20170260451-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-09-14 US disclosed
US-20170226420-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-10 US disclosed
US-9695361-B2 Liquid crystal composition and liquid crystal display element using the same DIC CORPORATION (JP) 2017-07-04 US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 US disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 US disclosed
US-9637684-B2 Composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-05-02 US disclosed
US-9624434-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-04-18 US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 US disclosed