Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 14/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458620 | 0.91 | DPP4 (0.35) | APPDPP4DPP9DPP7DPP8 | |
| SCHEMBL18458840 | 0.88 | APP (0.36) | APPCYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL18458722 | 0.87 | DPP4 (0.36) | APPDPP4DPP9DPP7DPP8 | |
| SCHEMBL19176251 | 0.85 | KDM1A (0.36) | APP | |
| SCHEMBL18458902 | 0.85 | DPP4 (0.34) | APPCYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL19229037 | 0.84 | APP (0.35) | APPCYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL18458756 | 0.84 | DPP4 (0.38) | DPP4DPP9DPP7DPP8 | |
| SCHEMBL18458593 | 0.84 | APP (0.41) | APPCYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL18866787 | 0.83 | FASN (0.41) | APPCYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL17552977 | 0.83 | CYP3A4 (0.38) | APPCYP3A4CYP2C9CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822304-B2 | Liquid crystal composition and liquid crystal display element containing the same | DIC CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |