SCHEMBL18462016

SCHEMBL18462016

BC(B)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1183503 0.77
SCHEMBL23733042 0.77
SCHEMBL29613354 0.77
SCHEMBL83931 0.77
Ammonia Solution, Strong SCHEMBL1727902 0.72
SCHEMBL18392601 0.72
SCHEMBL84518 0.72
SCHEMBL9560615 0.72
SCHEMBL2666224 0.72
SCHEMBL25417806 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
US-20230233700-A1 METHODS FOR PREPARING ANTIBODY DRUG CONJUGATES GENENTECH, INC. (US) 2023-07-27 US disclosed
US-11547762-B2 Methods for preparing antibody drug conjugates GENENTECH, INC. (US) 2023-01-10 US disclosed
US-20220324819-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2022-10-13 US disclosed
US-11357828-B2 Releasable GLP-1 conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2022-06-14 US disclosed
US-20220169664-A1 MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESS FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-06-02 US disclosed
US-20220118055-A1 RELEASABLE GLP-1 CONJUGATES FISH & RICHARDSON PC 2022-04-21 US disclosed
US-10941115-B2 Kinase inhibitors OXULAR ACQUISITIONS LIMITED (GB) 2021-03-09 US disclosed
US-20210052587-A1 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY MEDICINSK FORSKNING (SE) 2021-02-25 US disclosed
US-9796742-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-10-24 US disclosed
US-9790209-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-10-17 US disclosed
US-9790174-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-10-17 US disclosed
US-9783556-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-10-10 US disclosed
US-9771354-B2 Pyrazole p38 map kinase inhibitors RESPIVERT LTD. (GB) 2017-09-26 US disclosed
US-9771353-B2 Kinase inhibitors based upon N-alkyl pyrazoles TOPIVERT PHARMA LIMITED (GB) 2017-09-26 US disclosed
US-20170253563-A1 KINASE INHIBITORS OXULAR ACQUISITIONS LIMITED (GB) 2017-09-07 US disclosed
US-9751837-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-09-05 US disclosed
US-9732063-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-08-15 US disclosed
US-20170029378-A1 KINASE INHIBITOR OXULAR ACQUISITIONS LIMITED (GB) 2017-02-02 US disclosed