Fluoride

Fluoride

SCHEMBL184628

CCCCCCCCCCCCC1(CCCCCCCCCCCC)CNCCO1.F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11515632 1.00 SIRT2 (0.33) SIRT2
SCHEMBL1961598 1.00 SIRT2 (0.33) SIRT2
SCHEMBL18222228 1.00 SIRT2 (0.33) SIRT2
SCHEMBL28651557 1.00 SIRT2 (0.33) SIRT2
SCHEMBL29069414 1.00 SIRT2 (0.33) SIRT2
Hydrochloric Acid SCHEMBL28376541 0.96 SIRT2 (0.30) SIRT2
Bromide SCHEMBL28372064 0.96 SIRT2 (0.30) SIRT2
SCHEMBL28052641 0.95
SCHEMBL6262047 0.93 SIRT2 (0.32) SIRT2
SCHEMBL1962071 0.92 HSD17B10 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363991-A1 Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2023-11-16 US claimed
EP-4203900-A1 ORAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2023-07-05 EP claimed
EP-4199887-A1 ORAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2023-06-28 EP claimed
US-20220401321-A1 Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2022-12-22 US claimed
WO-2022251223-A1 ORAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2022-12-01 WO claimed
WO-2022251228-A1 ORAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2022-12-01 WO claimed
EP-3370830-B1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2020-02-05 EP claimed
EP-3370830-A1 ORAL CARE COMPOSITIONS AND METHODS Colgate-Palmolive Company (US) 2018-09-12 EP claimed
WO-2017100265-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE-PALMOLIVE COMPANY (US) 2017-06-15 WO claimed
EP-2046270-B1 HIGH FLUORIDE ION ORAL CARE COMPOSITION AND METHOD FOR MAINTAINING ANTICARIES ACTIVITY COLGATE PALMOLIVE CO (US) 2017-06-07 EP claimed
US-8506698-B2 Oral compositions and methods COLGATE-PALMOLIVE COMPANY (US) 2013-08-13 US claimed
US-20110033394-A1 ORAL COMPOSITIONS AND METHODS COLGATE-PALMOLIVE COMPANY (US) 2011-02-10 US claimed
EP-2280685-A1 ORAL COMPOSITIONS COMPRISING SHELLAC WAX AND BLEACHED SHELLAC FOR USE IN STOMATOLOGY AND DENTAL CARE Colgate-Palmolive Company (US) 2011-02-09 EP claimed
EP-2265242-A1 HIGH FLUORIDE ION RECOVERY COMPOSITIONS Colgate-Palmolive Company (US) 2010-12-29 EP claimed
WO-2009124311-A1 ORAL COMPOSITIONS COMPRISING SHELLAC WAX AND BLEACHED SHELLAC FOR USE IN STOMATOLOGY AND DENTAL CARE COLGATE-PALMOLIVE COMPANY (US) 2009-10-08 WO claimed
WO-2009117644-A1 HIGH FLUORIDE ION RECOVERY COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2009-09-24 WO claimed
US-20090238777-A1 High Fluoride Ion Recovery Compositions COLGATE-PALMOLIVE COMPANY (US) 2009-09-24 US claimed
EP-2046270-A2 HIGH FLUORIDE ION ORAL CARE COMPOSITION AND METHOD FOR MAINTAINING ANTICARIES ACTIVITY Colgate-Palmolive Company (US) 2009-04-15 EP claimed
WO-2008005688-A2 HIGH FLUORIDE ION ORAL CARE COMPOSITION AND METHOD FOR MAINTAINING ANTICARIES ACTIVITY COLGATE-PALMOLIVE COMPANY (US) 2008-01-10 WO claimed
US-20080003187-A1 High fluoride ion oral care composition and method for maintaining anticaries activity COLGATE-PALMOLIVE COMPANY 2008-01-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230363991-A1 Oral Care Compositions DSC1, SLC6A12, OTC SIRT2 1200/4885
US-20220401321-A1 Oral Care Compositions TUBGCP3, TUBGCP4, TUBGCP2 SIRT2 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.