Fluoride Ion

Fluoride Ion

SCHEMBL184629

CCCCCCCCCCCC[N+]1(CCCCCCCCCCCC)CCOCC1.[F-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.41
THRB P10828 2/20 0.35
TSHR P16473 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.34
EPHX1 P07099 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3275678 0.98 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
SCHEMBL10537448 0.98 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
SCHEMBL1961599 0.98 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
SCHEMBL4071466 0.98 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
SCHEMBL11515636 0.98 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
Water SCHEMBL26184970 0.96 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
SCHEMBL8965122 0.96 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
Hydrochloric Acid SCHEMBL11781908 0.96 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
Water SCHEMBL31291058 0.96 CDC25A (0.41) CDC25ATHRBTSHRCTDSP1EPHX1
SCHEMBL29975144 0.94 CDC25A (0.40) CDC25ATHRBTSHRCTDSP1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363991-A1 Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2023-11-16 US claimed
EP-4203900-A1 ORAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2023-07-05 EP claimed
EP-4199887-A1 ORAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2023-06-28 EP claimed
US-20220401321-A1 Oral Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2022-12-22 US claimed
WO-2022251223-A1 ORAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2022-12-01 WO claimed
WO-2022251228-A1 ORAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2022-12-01 WO claimed
EP-3370830-B1 ORAL CARE COMPOSITIONS AND METHODS COLGATE PALMOLIVE CO (US) 2020-02-05 EP claimed
EP-3370830-A1 ORAL CARE COMPOSITIONS AND METHODS Colgate-Palmolive Company (US) 2018-09-12 EP claimed
WO-2017100265-A1 ORAL CARE COMPOSITIONS AND METHODS COLGATE-PALMOLIVE COMPANY (US) 2017-06-15 WO claimed
EP-2046270-B1 HIGH FLUORIDE ION ORAL CARE COMPOSITION AND METHOD FOR MAINTAINING ANTICARIES ACTIVITY COLGATE PALMOLIVE CO (US) 2017-06-07 EP claimed
US-8506698-B2 Oral compositions and methods COLGATE-PALMOLIVE COMPANY (US) 2013-08-13 US claimed
US-20110033394-A1 ORAL COMPOSITIONS AND METHODS COLGATE-PALMOLIVE COMPANY (US) 2011-02-10 US claimed
EP-2280685-A1 ORAL COMPOSITIONS COMPRISING SHELLAC WAX AND BLEACHED SHELLAC FOR USE IN STOMATOLOGY AND DENTAL CARE Colgate-Palmolive Company (US) 2011-02-09 EP claimed
EP-2265242-A1 HIGH FLUORIDE ION RECOVERY COMPOSITIONS Colgate-Palmolive Company (US) 2010-12-29 EP claimed
WO-2009124311-A1 ORAL COMPOSITIONS COMPRISING SHELLAC WAX AND BLEACHED SHELLAC FOR USE IN STOMATOLOGY AND DENTAL CARE COLGATE-PALMOLIVE COMPANY (US) 2009-10-08 WO claimed
WO-2009117644-A1 HIGH FLUORIDE ION RECOVERY COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2009-09-24 WO claimed
US-20090238777-A1 High Fluoride Ion Recovery Compositions COLGATE-PALMOLIVE COMPANY (US) 2009-09-24 US claimed
EP-2046270-A2 HIGH FLUORIDE ION ORAL CARE COMPOSITION AND METHOD FOR MAINTAINING ANTICARIES ACTIVITY Colgate-Palmolive Company (US) 2009-04-15 EP claimed
WO-2008005688-A2 HIGH FLUORIDE ION ORAL CARE COMPOSITION AND METHOD FOR MAINTAINING ANTICARIES ACTIVITY COLGATE-PALMOLIVE COMPANY (US) 2008-01-10 WO claimed
US-20080003187-A1 High fluoride ion oral care composition and method for maintaining anticaries activity COLGATE-PALMOLIVE COMPANY 2008-01-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230363991-A1 Oral Care Compositions DSC1, SLC6A12, OTC CDC25A 3980/4885THRB 647/4885TSHR 1621/4885
US-20220401321-A1 Oral Care Compositions TUBGCP3, TUBGCP4, TUBGCP2 CDC25A 4104/4885THRB 1379/4885TSHR 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.