Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.38 |
| ▸ | USP1 | O94782 | 3/20 | 0.38 |
| ▸ | WDR48 | Q8TAF3 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22037903 | 0.99 | PDK2 (0.46) | PDK2CYP2A6KIF11CYP17A1CYP19A1 | |
| SCHEMBL18463301 | 0.99 | PDK2 (0.46) | PDK2CYP2A6KIF11CYP17A1CYP19A1 | |
| SCHEMBL22038354 | 0.94 | PDK2 (0.43) | PDK2CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL22037463 | 0.94 | PDK2 (0.49) | PDK2CYP2A6KIF11CYP17A1CYP19A1 | |
| SCHEMBL22039107 | 0.94 | PDK2 (0.49) | PDK2CYP2A6KIF11CYP17A1CYP19A1 | |
| SCHEMBL20465205 | 0.91 | PDK2 (0.46) | PDK2CYP2A6CYP17A1CYP19A1CYP11B1 | |
| SCHEMBL22038381 | 0.91 | PDK2 (0.49) | PDK2CYP19A1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22039069 | 0.91 | PDK2 (0.46) | PDK2CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL22038363 | 0.91 | PDK2 (0.46) | PDK2CYP2A6KIF11CYP17A1CYP19A1 | |
| SCHEMBL18463283 | 0.90 | PDK2 (0.45) | PDK2CYP2A6KIF11CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328841-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-10-11 | — | — | EP | disclosed |
| US-20180222872-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180222872-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| WO-2017016630-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222872-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, NES, PIR | PDK2 364/4885CYP2A6 3974/4885KIF11 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.