Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18464728 | 0.86 | TACR1 (0.39) | TNKSTNKS2KIF11MAPTTRPV1 | |
| SCHEMBL18426863 | 0.86 | GPR84 (0.39) | GPR84SMN1; SMN2TP53TNKSTNKS2 | |
| SCHEMBL18425737 | 0.86 | GPR84 (0.44) | GPR84SMN1; SMN2TP53TNKSTNKS2 | |
| SCHEMBL18464716 | 0.81 | CYP1A2 (0.43) | GPR84SMN1; SMN2TNKSTNKS2KMT2A | |
| SCHEMBL18464722 | 0.78 | EGFR (0.40) | MEN1KMT2AAKT1 | |
| SCHEMBL18425832 | 0.76 | DHODH (0.40) | KDM4EMAPTHTTNPSR1AKT1 | |
| SCHEMBL18464720 | 0.76 | CYP11B1 (0.37) | NPC1LMNAKDM4EMAPTHTT | |
| SCHEMBL18464723 | 0.74 | TDP1 (0.48) | KDM4EHTTNPSR1GPR3 | |
| SCHEMBL18425748 | 0.74 | PIK3CD (0.37) | TRPM8TNFKCNH2KDM4EGPR3 | |
| SCHEMBL18464729 | 0.73 | CHEK1 (0.37) | KDM4EGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328859-B1 | 3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV) | BOEHRINGER INGELHEIM INT (DE) | 2020-06-03 | — | — | EP | disclosed |
| US-20190002436-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2019-01-03 | — | — | US | disclosed |
| WO-2017018924-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2017-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002436-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | NR0B1, NR1I3, SCARB1 | GPR84 394/4885SMN1; SMN2 868/4885TP53 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.