Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 4/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18680425 | 0.98 | HTT (0.37) | HTTCA1CA2CA9HSP90AA1 | |
| SCHEMBL17563604 | 0.90 | HTT (0.42) | HTTCA1CA2CA9HSP90AA1 | |
| SCHEMBL17576144 | 0.90 | HSP90AA1 (0.40) | HTTHSP90AA1ABCB1LMNAALDH1A1 | |
| SCHEMBL17826478 | 0.87 | HTT (0.49) | HTTCA1CA2CA9HSP90AA1 | |
| SCHEMBL18466767 | 0.87 | HTT (0.49) | HTTCA1CA2CA9HSP90AA1 | |
| SCHEMBL18466796 | 0.85 | CXCL12 (0.41) | HTTCA1CA2CA9LMNA | |
| SCHEMBL18466738 | 0.85 | HSP90AA1 (0.46) | HTTHSP90AA1ABCB1LMNAALDH1A1 | |
| SCHEMBL18679951 | 0.85 | HSP90AA1 (0.46) | HTTCA1CA2CA9HSP90AA1 | |
| SCHEMBL17826463 | 0.85 | HSP90AA1 (0.46) | HTTHSP90AA1ABCB1LMNAALDH1A1 | |
| SCHEMBL18680442 | 0.85 | CYP1A2 (0.41) | HTTCA1CA2CA9HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A9 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-04-20 | — | — | WO | disclosed |
| US-20170088671-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-03-30 | — | — | US | disclosed |
| US-9562137-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2017-02-07 | — | — | US | disclosed |