SCHEMBL18471963

SCHEMBL18471963

c1ccc2c(c1)Cc1cc(-c3nc(-c4ccc5c(c4)Cc4ccccc4-5)nc(-c4ccc5c(c4)Cc4ccccc4-5)n3)ccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
KDM4E B2RXH2 3/20 0.53
LMNA P02545 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 1/20 0.53
HPGD P15428 1/20 0.53
SRD5A2 P31213 1/20 0.51
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
PYGL P06737 1/20 0.46
CYP3A4 P08684 2/20 0.45
CYP1A2 P05177 2/20 0.45
TDP1 Q9NUW8 1/20 0.44
HTR2C P28335 2/20 0.44
HTR2B P41595 2/20 0.44
DRD2 P14416 1/20 0.44
ADRA1D P25100 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25859172 0.95 SRD5A2 (0.51) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL23255243 0.95 SRD5A2 (0.51) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL22068174 0.90 SRD5A2 (0.47) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL23919082 0.90 SRD5A2 (0.47) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL25945304 0.89 SRD5A2 (0.46) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL6764711 0.89 MEN1 (0.47) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL27389587 0.87 SRD5A2 (0.45) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL26033870 0.87 SRD5A2 (0.45) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL25859167 0.87 MEN1 (0.51) MAPTKDM4ELMNANPC1RAB9A
SCHEMBL3414807 0.86 ALDH1A1 (0.63) MAPTKDM4ELMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022172551-A1 LAMINATE, LAYER-FORMING COMPOSITION, LAYER, METHOD FOR MANUFACTURING LAMINATE, AND ELECTRONIC ELEMENT JSR株式会社 2022-08-18 WO disclosed
US-11243468-B2 Composition for resist underlayer film formation, resist underlayer film and formation method thereof, and patterned substrate production method JSR CORPORATION (JP) 2022-02-08 US disclosed
US-20170040536-A1 DIBENZOBOROLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170040536-A1 DIBENZOBOROLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CYP1B1, DDT, SLC19A2 MAPT 2935/4885KDM4E 4234/4885LMNA 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.