Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.55 |
| ▸ | DTYMK | P23919 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27000489 | 1.00 | TERT (0.55) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL25580372 | 1.00 | TERT (0.55) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL26860402 | 1.00 | TERT (0.55) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL26221013 | 1.00 | TERT (0.55) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL27103916 | 1.00 | TERT (0.55) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL26860127 | 1.00 | TERT (0.55) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL27000729 | 1.00 | TERT (0.55) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL25456890 | 0.97 | TERT (0.53) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL18993187 | 0.97 | TERT (0.53) | TERTDTYMKF2POLBTK1 | |
| SCHEMBL17231693 | 0.97 | TERT (0.53) | TERTDTYMKF2POLBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037410-A1 | COMPOSITIONS FOR MODULATING SOD-1 EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-02-09 | — | — | US | disclosed |