Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14948211 | 0.84 | MAPK1 (0.41) | ACHEKDM4EMAPTMAPK1TDP1 | |
| SCHEMBL16489401 | 0.83 | KMT2A (0.39) | ACHEESR1ESR2KDM4EMAPT | |
| SCHEMBL16489400 | 0.83 | PRNP (0.39) | ACHEKDM4EMAPTMAPK1TDP1 | |
| SCHEMBL30849704 | 0.83 | CYP1A2 (0.40) | KDM4EMAPK1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23427763 | 0.80 | CA1 (0.35) | ACHEKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30662421 | 0.80 | TNKS (0.46) | ACHELMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL22978415 | 0.80 | TNKS (0.46) | ACHELMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29354925 | 0.80 | ACHE (0.56) | ACHEESR1ESR2KDM4EMAPT | |
| SCHEMBL36757 | 0.80 | ACHE (0.56) | ACHEESR1ESR2KDM4EMAPT | |
| SCHEMBL23428190 | 0.79 | ENPP1 (0.34) | ACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9564597-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |