Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.68 |
| ▸ | MRGPRX2 | Q96LB1 | 3/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12006856 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL16731962 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL18458103 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL10079544 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL16731963 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL18458105 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL12006829 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL553979 | 1.00 | OPRM1 (0.68) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL18720200 | 0.91 | OPRM1 (0.62) | OPRM1OPRD1OPRK1MRGPRX2PDE4D | |
| SCHEMBL20077640 | 0.91 | OPRM1 (0.64) | OPRM1OPRD1OPRK1MRGPRX2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562014-B2 | (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof | MALLINCKRODT LLC (US) | 2017-02-07 | — | — | US | disclosed |