Sugi Predict

Sugi Predict / Compounds / SCHEMBL18477

SCHEMBL18477

SCHEMBL18477

CC(C)(C)OC(=O)CC[C@H](N)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.43
▸ NOS1 P29475 2/20 0.38
▸ NOS3 P29474 1/20 0.38
▸ NOS2 P35228 1/20 0.38
▸ SLC1A1 P43005 2/20 0.35
▸ HDAC3 O15379 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ HDAC8 Q9BY41 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ CYP1A2 P05177 2/20 0.33
▸ GRM8 O00222 1/20 0.33
▸ GRM6 O15303 1/20 0.33
▸ GRIN2D O15399 1/20 0.33
▸ GRIN3B O60391 1/20 0.33
▸ GSR P00390 1/20 0.33
▸ GRIK1 P39086 1/20 0.33
▸ GRM5 P41594 1/20 0.33
▸ GRIA1 P42261 1/20 0.33
▸ GRIA2 P42262 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1841835 1.00 LTA4H (0.43) LTA4HNOS1NOS3NOS2SLC1A1
SCHEMBL1654337 1.00 LTA4H (0.43) LTA4HNOS1NOS3NOS2SLC1A1
Hydrochloric Acid SCHEMBL4654220 0.98 LTA4H (0.42) LTA4HNOS1NOS3NOS2SLC1A1
SCHEMBL6893763 0.98 LTA4H (0.42) LTA4HNOS1NOS3NOS2SLC1A1
Hydrochloric Acid SCHEMBL18476 0.98 LTA4H (0.42) LTA4HNOS1NOS3NOS2SLC1A1
Water SCHEMBL27596082 0.98 LTA4H (0.42) LTA4HNOS1NOS3NOS2SLC1A1
Water SCHEMBL3912787 0.98 LTA4H (0.42) LTA4HNOS1NOS3NOS2SLC1A1
Hydrochloric Acid SCHEMBL1517836 0.98 LTA4H (0.42) LTA4HNOS1NOS3NOS2SLC1A1
SCHEMBL18744647 0.90 LTA4H (0.40) LTA4HNOS1NOS3NOS2SLC1A1
SCHEMBL23416460 0.89 LTA4H (0.39) LTA4HNOS1NOS3NOS2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367332-A1 PSMA-TARGETED RADIOACTIVE METAL COMPLEX CONTAINING NITROAROMATIC HETEROCYCLIC GROUP AND PREPARATION METHOD UNIV BEIJING NORMAL (CN) 2025-12-04 — — US claimed
CN-119301141-A Compound of double-targeting tumor cells, preparation method and application thereof 中国医学科学院北京协和医院 2025-01-10 — — CN claimed
WO-2024255776-A1 AMPHIPHILIC POLYMER LY0016, AND SYNTHESIS AND USE THEREOF 北京良远生物医药研究有限公司 2024-12-19 — — WO claimed
CN-118546192-A Cordycepin prodrug for resisting cancer, preparation method and application thereof 中国科学院苏州生物医学工程技术研究所 2024-08-27 — — CN claimed
CN-118546180-A Small molecule prodrug of clofarabine, preparation method and application thereof 中国科学院苏州生物医学工程技术研究所 2024-08-27 — — CN claimed
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 — — CN claimed
CN-118005916-A Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof 四川大学 2024-05-10 — — CN claimed
WO-2023231452-A1 PSMA-TARGETING RADIOACTIVE METAL COMPLEX CONTAINING NITRO AROMATIC HETEROCYCLIC GROUP AND PREPARATION THEREOF 北京师范大学 2023-12-07 — — WO claimed
CN-116606405-A Anisotropic hydrogel material and preparation method thereof 沧州市天津工业大学研究院 2023-08-18 — — CN claimed
CN-116507630-A PSMA targeted radioactive metal complex containing nitro aromatic heterocyclic group and preparation thereof 北京师范大学 2023-07-28 — — CN claimed
CN-114907546-B Multifunctional polyurea acid ester derivative and preparation method and application thereof 四川大学 2023-06-02 — — CN claimed
CN-115368234-A Synthesis method of important intermediate of Somaloutide side chain 淄博矿业集团有限责任公司 2022-11-22 — — CN claimed
CN-109384715-B Preparation method of small molecule inhibitor of prostate specific membrane antigen 复旦大学附属肿瘤医院 2021-09-03 — — CN claimed
CN-110982012-B Amphoteric acrylamide polymer flocculant and preparation method thereof 江西科技师范大学 2021-08-06 — — CN claimed
CN-109134602-B Solid phase preparation method of efficient prostate specific membrane antigen ligand PSMA-617 兰州大学 2021-07-02 — — CN claimed
CN-110272468-B Preparation and application of prostate specific membrane antigen small molecule inhibitor and radionuclide complex thereof 上海益泰医药科技有限公司 2020-12-08 — — CN claimed
CN-110982012-A Novel amphoteric acrylamide polymer flocculant and preparation method thereof 江西科技师范大学 2020-04-10 — — CN claimed
US-20120148631-A1 PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2012-06-14 — — US claimed
EP-1391449-A1 Hydrolysis of amino acid diesters PCBU Services, Inc. (US) 2004-02-25 — — EP claimed
US-20040030177-A1 Hydrolysis of amino acid diesters PCBU SERVICES, INC. 2004-02-12 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148631-A1 PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY PARN, PUF60, PARG LTA4H 4344/4885NOS1 3652/4885NOS3 2492/4885
US-20250367332-A1 PSMA-TARGETED RADIOACTIVE METAL COMPLEX CONTAINING NITROAROMATIC HETEROCYCLIC GROUP AND PREPARATION METHOD PSMA1, PSMA2, PSMA7 LTA4H 2219/4885NOS1 238/4885NOS3 1562/4885
US-20040030177-A1 Hydrolysis of amino acid diesters DNPEP, ANPEP, DAO LTA4H 208/4885NOS1 235/4885NOS3 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.