Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077911 | 0.82 | — | — | |
| SCHEMBL18477011 | 0.74 | — | — | |
| SCHEMBL4827904 | 0.72 | — | — | |
| SCHEMBL14378315 | 0.71 | ESR1 (0.32) | — | |
| SCHEMBL237734 | 0.70 | CYP1A2 (0.37) | — | |
| SCHEMBL12086341 | 0.70 | LIPA (0.34) | LIPA | |
| SCHEMBL17622937 | 0.70 | LIPA (0.34) | LIPA | |
| SCHEMBL17428785 | 0.70 | LIPA (0.34) | LIPA | |
| SCHEMBL24325564 | 0.69 | CYP1A2 (0.36) | LIPA | |
| SCHEMBL14646599 | 0.69 | THRA (0.39) | LIPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024018-A1 | MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, INC. (US) | 2017-02-09 | — | — | WO | disclosed |