Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18477800 | 0.89 | TLR7 (0.55) | TLR7LMNAPOLBADORA2AHRH2 | |
| Hydrochloric Acid SCHEMBL3191333 | 0.89 | TLR7 (0.54) | TLR7LMNAPOLBADORA2AHRH2 | |
| SCHEMBL18477813 | 0.86 | TLR7 (0.40) | TLR7LMNAPOLBADORA2AHRH2 | |
| SCHEMBL3185905 | 0.84 | EGLN3 (0.41) | TLR7LMNAPOLBADORA2AHRH2 | |
| Sarcosine SCHEMBL18477807 | 0.84 | TLR7 (0.46) | TLR7LMNAPOLBADORA2AHRH2 | |
| Hydrochloric Acid SCHEMBL3188640 | 0.83 | EGLN3 (0.41) | TLR7LMNAPOLBADORA2AHRH2 | |
| SCHEMBL3187479 | 0.83 | NPC1 (0.41) | TLR7LMNAPOLBADORA2AHRH2 | |
| Hydrochloric Acid SCHEMBL3191447 | 0.82 | NPC1 (0.40) | TLR7LMNAPOLBADORA2AHRH2 | |
| SCHEMBL18477818 | 0.82 | IKBKB (0.40) | TLR7LMNAPOLBADORA2AHRH2 | |
| SCHEMBL18477810 | 0.81 | GRK6 (0.41) | TLR7LMNAPOLBADORA2AHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567329-B2 | High penetration prodrug compositions of 1H-imidazo[4,5-c]quinolin-4-amines and 1H-imidazo[4,5-c]quinolin-4-amine-related compounds and uses thereof | TECHFIELDS PHARMA CO., LTD. (CN) | 2017-02-14 | — | — | US | claimed |