Sarcosine

Sarcosine

SCHEMBL18477807

CNCC(=O)O.NC(=O)c1nc2ccccc2c2c1ncn2CC(O)CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 4/20 0.46
LMNA P02545 2/20 0.46
POLB P06746 2/20 0.46
ADORA2A P29274 2/20 0.46
HRH2 P25021 1/20 0.46
ADRA1D P25100 1/20 0.46
HTR2A P28223 1/20 0.46
ADRA1A P35348 1/20 0.46
NUDT1 P36639 1/20 0.46
HTR2B P41595 1/20 0.46
PDE4D Q08499 1/20 0.46
KCNH2 Q12809 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.35
AHCY P23526 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.33
MMP9 P14780 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
TGFBR1 P36897 2/20 0.33
AGER Q15109 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sarcosine SCHEMBL18477799 0.89 TLR7 (0.59) TLR7LMNAPOLBADORA2AHRH2
Sarcosine SCHEMBL3191326 0.88 TLR7 (0.58) TLR7LMNAPOLBADORA2AHRH2
Sarcosine SCHEMBL18477812 0.86 TLR7 (0.43) TLR7LMNAPOLBADORA2AHRH2
Sarcosine SCHEMBL3185898 0.84 EGLN3 (0.47) TLR7LMNAPOLBADORA2AHRH2
SCHEMBL18477808 0.84 TLR7 (0.43) TLR7LMNAPOLBADORA2AHRH2
Sarcosine SCHEMBL3188629 0.83 EGLN3 (0.46) TLR7LMNAPOLBADORA2AHRH2
Sarcosine SCHEMBL3187476 0.82 TLR7 (0.41) TLR7LMNAPOLBADORA2AHRH2
Sarcosine SCHEMBL3191440 0.82 TLR7 (0.41) TLR7LMNAPOLBADORA2AHRH2
Sarcosine SCHEMBL18477817 0.81 IKBKB (0.40) TLR7LMNAPOLBADORA2AHRH2
SCHEMBL487883 0.81 TLR7 (0.68) TLR7LMNAPOLBADORA2AHRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9567329-B2 High penetration prodrug compositions of 1H-imidazo[4,5-c]quinolin-4-amines and 1H-imidazo[4,5-c]quinolin-4-amine-related compounds and uses thereof TECHFIELDS PHARMA CO., LTD. (CN) 2017-02-14 US claimed