SCHEMBL1847797

SCHEMBL1847797

C[C@H](CCC1CCN(C(=O)OC(C)(C)C)CC1)Oc1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1574993 1.00 GPR119 (0.69) GPR119
SCHEMBL1844435 0.87 GPR119 (0.51) GPR119
SCHEMBL1575744 0.83 GPR119 (0.89) GPR119
SCHEMBL1574955 0.82 GPR119 (1.00) GPR119
SCHEMBL1576011 0.81 GPR119 (0.63) GPR119
SCHEMBL1840724 0.81 GPR119 (0.45) GPR119
SCHEMBL26635590 0.80 GPR119 (0.47) GPR119
SCHEMBL26635583 0.80 GPR119 (0.47) GPR119
SCHEMBL26636540 0.80 GPR119 (0.47) GPR119
SCHEMBL26636545 0.80 GPR119 (0.47) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321305-A1 HETEROCYCLIC GPCR AGONISTS Prosidion Limited (GB) 2011-05-18 EP disclosed
WO-2010004348-A1 HETEROCYCLIC GPCR AGONISTS PROSIDION LIMITED (GB) 2010-01-14 WO disclosed